Discontinue use if hypersensitivity reactions & paradoxical bronchospasm occurs. Not to be used for acute asthma & bronchospasm episodes. CV disorders (CAD, acute MI, cardiac arrhythmias, HTN), convulsive disorders or thyrotoxicosis, unusually responsive to β
2-adrenergic agonists; unstable ischaemic heart disease, history of MI w/in last 12 mth, NYHA class III/IV left ventricular failure, arrhythmia, uncontrolled HTN, cerebrovascular disease; known or suspected QT interval prolongation or patients treated w/ medicinal products affecting QT interval; hypokalaemia; hyperglycaemia, type I or uncontrolled type II DM; narrow-angle glaucoma or urinary retention; pulmonary TB, chronic or untreated infections. Systemic effects eg, Cushing's syndrome, Cushingoid features, adrenal suppression, decreased bone mineral density, cataracts, glaucoma, psychological or behavioural effects, psychomotor hyperactivity, sleep disorders, anxiety, depression or aggression; visual disturbance. Rinse mouth or gargle w/ water w/o swallowing to reduce risk of oropharyngeal candida infection. Avoid abrupt w/drawal. High-dose & prolonged use. Not to be used in galactose intolerance, total lactase deficiency or glucose-galactose malabsorption. Severe renal (GFR <30 mL/min/1.73 m
2) or hepatic impairment; ESRD requiring dialysis. Pregnancy & lactation. Childn <18 yr; growth retardation in childn & adolescents.
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